Compositions and methods for inhibiting PDGFRβ and VEGF-A

Disclosed are antagonists of PDGF receptor β (PDGFRβ) and VEGF-A, including neutralizing anti-PDGFRβ and anti-VEGF-A antibodies, as well as related compositions and methods. Anti-PDGFRβ and anti-VEGF-A antibodies disclosed herein include bispecific antibodies capable of binding and neutralizing both...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Presnell Scott R, Gilbertson Debra G, Sivakumar Pallavur V, Mabry George R, Snavely Marshall D, Yi Eugene C, Yao Yue
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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