Uracil derivatives and use thereof

Disclosed are uracil derivatives of the formula (I): wherein R1, R2, R3, and X are as defined herein, and use thereof as therapeutic agents. The uracil derivatives are used in particular together with a cytostatic agent for suppressing or reducing resistance building up on cytostatic treatment.

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Hauptverfasser: FUHRER MARTIN, EGER KURT, HEINRICH JORGRISTIAN, KLEMM MATTHIAS, FAHRIG RUDOLF, HEINZE NICOLE
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creator FUHRER MARTIN
EGER KURT
HEINRICH JORGRISTIAN
KLEMM MATTHIAS
FAHRIG RUDOLF
HEINZE NICOLE
description Disclosed are uracil derivatives of the formula (I): wherein R1, R2, R3, and X are as defined herein, and use thereof as therapeutic agents. The uracil derivatives are used in particular together with a cytostatic agent for suppressing or reducing resistance building up on cytostatic treatment.
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subjects CHEMISTRY
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
title Uracil derivatives and use thereof
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