Monoclonal antibodies to human immunodeficiency virus and uses thereof

The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In...

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Bibliographische Detailangaben
Hauptverfasser: LOU SHENG C, KONRATH JOHN G, SCHEFFEL JAMES W, TYNER JOAN D, HUNT JEFFREY C, QIU XIAOXING
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.