Substituted pyrido[2,3-B]pyrazines as IP receptor agonists

The present invention provides substituted pyrido[2,3-b]pyrazines which activate the IP receptor. Activating the IP receptor signaling pathway is useful to treat many forms of PAH, pulmonary fibrosis and exert beneficial effects in fibrotic conditions of various organs in animal models and in patien...

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Bibliographische Detailangaben
Hauptverfasser: MCKEOWN STEPHEN CARL, CHARLTON STEVEN JOHN, LEBLANC CATHERINE
Format: Patent
Sprache:eng
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