Multilayer preform obtained by electro-spinning, method for producing a preform as well as use thereof

The invention relates a multilayer preform obtained by electro-spinning, which preform is suitable as a scaffold for a prosthesis, which preform comprises at least one layer of microfibers and at least one layer of nanofibers, wherein the pore size of the at least one layer of microfibers is in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BAAIJENS FRANCISCUS PETRUS THOMAS, RUBBENS MIRJAM PETRONELLA, COX MARTIJN ANTONIUS JOHANNES
Format:	Patent
Sprache:	eng
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS BRAIDING COTTON-WOOL DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS,NON-WOVEN FABRICS FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE KNITTING LACE-MAKING MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARYMATERIAL MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OFARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES ORRIBBONS MEDICAL OR VETERINARY SCIENCE NATURAL OR ARTIFICIAL THREADS OR FIBRES NON-WOVEN FABRICS ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES SPINNING TEXTILES TREATMENT OR PROTECTION OF EYES OR EARS TRIMMINGS WADDING
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Beschreibung
Zusammenfassung:	The invention relates a multilayer preform obtained by electro-spinning, which preform is suitable as a scaffold for a prosthesis, which preform comprises at least one layer of microfibers and at least one layer of nanofibers, wherein the pore size of the at least one layer of microfibers is in the range of 1-300 micrometer and in that the pore size of the at least one layer of nanofibers is in the range of 1-300 micrometer. The present invention also relates to a method of producing said preform. The present invention also relates to the use of the present preform as a substrate for growing human or animal tissue thereon. The present invention furthermore relates to a method for growing human or animal tissue on a substrate, wherein the present preform is used as the substrate.