Beta-lactamase inhibitors

Aryl substituted diazabicyclooctanes (DBO) compounds that inhibit -lactamases of class A, class C or class D and potentiate -lactam antibiotics are disclosed. In particular, this disclosure provides DBO compounds that, when used in the disclosed Synergy MIC Assay with a -lactam antibiotic at a fixed...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	METCALF, III CHESTER A, BUSCH ROBERT, ALEXANDER DYLAN C, DOLLE ROLAND E, YIN NING, GU YU GUI, HE YONG, CROSS JASON B
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
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