Fused imidazole derivative

Fused imidazole derivative

Provided is a novel compound which shows an antagonistic effect against T-type calcium channels, and is useful as a pharmaceutical product. A compound represented by general formula (I), and a pharmaceutical agent containing the same, are disclosed: wherein n represents the number of nitrogen atoms...

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Hauptverfasser: TAKAYANAGI KOICHI, SHIMONO RYUTARO, NAGAYAMA TOMOYUKI, TAKASUGI HIROSHI, MASAKI HIDEKAZU, UCHINO YUJIRO
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Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator TAKAYANAGI KOICHI
SHIMONO RYUTARO
NAGAYAMA TOMOYUKI
TAKASUGI HIROSHI
MASAKI HIDEKAZU
UCHINO YUJIRO
description Provided is a novel compound which shows an antagonistic effect against T-type calcium channels, and is useful as a pharmaceutical product. A compound represented by general formula (I), and a pharmaceutical agent containing the same, are disclosed: wherein n represents the number of nitrogen atoms contained in the 6-membered fused aromatic ring, and is 0, 1 or 2; p represents the number of nitrogen atoms contained in the 6-membered aromatic ring, and is 0 or 1; X represents an oxygen atom, -SO2- or -N(R9)-; and R1 to R5 each represents a hydrogen atom or other substituents.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Fused imidazole derivative
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