Method and system for automated image analysis in cancer cells

A method of screening for the presence and/or extent of a pathology in a subject, the pathology characterized by an abnormal chromosomal component in a cell of the subject, comprising the steps of: contacting a biological sample comprising cell nuclei from said subject with, one or more distinguisha...

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Hauptverfasser: UPENDER MADHVI, ENDRESS GREGORY ANTON, LIGHT ELIZABETH, CAIN COLYN
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creator UPENDER MADHVI
ENDRESS GREGORY ANTON
LIGHT ELIZABETH
CAIN COLYN
description A method of screening for the presence and/or extent of a pathology in a subject, the pathology characterized by an abnormal chromosomal component in a cell of the subject, comprising the steps of: contacting a biological sample comprising cell nuclei from said subject with, one or more distinguishable labeled probes directed to at least one chromosomal sequence that characterizes the abnormality under conditions that promote hybridization of the one or more probes to the at least one sequence, automatically obtaining a representation of the one or more distinguishable labels hybridized to the chromosomal sequences, automatically analyzing the distribution and intensity of binding of the one or more labels in the representation to determine the presence and/or extent of an abnormal chromosomal component; and automatically reporting results of the analysis; wherein the steps are carried out without intervention by a human.
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subjects BEER
BIOCHEMISTRY
CALCULATING
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPUTING
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
COUNTING
ENZYMOLOGY
IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title Method and system for automated image analysis in cancer cells
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