17-(1′propenyl)-17-3′-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative
The invention relates to 17-(1′-propenyl)-17-3′-oxidoestra-4-en-3-one derivatives with the general chemical formula I, where the residues Z, R4, R6a, R6b, R7, R15, R16a, R16b and R18 have the meanings stated in Claim 1, and their solvates, hydrates and salts, including all stereoisomers of these com...
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| creator | MENGES FREDERIK KUHNKE JOACHIM RING SVEN FRENZEL THOMAS PRELLE KATJA BOHLMANN ROLF HÜBNER JAN KLAR ULRICH MUHN HANS PETER BORDEN STEFFEN |
| description | The invention relates to 17-(1′-propenyl)-17-3′-oxidoestra-4-en-3-one derivatives with the general chemical formula I, where the residues Z, R4, R6a, R6b, R7, R15, R16a, R16b and R18 have the meanings stated in Claim 1, and their solvates, hydrates and salts, including all stereoisomers of these compounds. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives, and in particular application in the aforementioned indications. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action. |
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The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives, and in particular application in the aforementioned indications. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; STEROIDS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150519&DB=EPODOC&CC=US&NR=9034856B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150519&DB=EPODOC&CC=US&NR=9034856B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MENGES FREDERIK</creatorcontrib><creatorcontrib>KUHNKE JOACHIM</creatorcontrib><creatorcontrib>RING SVEN</creatorcontrib><creatorcontrib>FRENZEL THOMAS</creatorcontrib><creatorcontrib>PRELLE KATJA</creatorcontrib><creatorcontrib>BOHLMANN ROLF</creatorcontrib><creatorcontrib>HÜBNER JAN</creatorcontrib><creatorcontrib>KLAR ULRICH</creatorcontrib><creatorcontrib>MUHN HANS PETER</creatorcontrib><creatorcontrib>BORDEN STEFFEN</creatorcontrib><title>17-(1′propenyl)-17-3′-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative</title><description>The invention relates to 17-(1′-propenyl)-17-3′-oxidoestra-4-en-3-one derivatives with the general chemical formula I, where the residues Z, R4, R6a, R6b, R7, R15, R16a, R16b and R18 have the meanings stated in Claim 1, and their solvates, hydrates and salts, including all stereoisomers of these compounds. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives, and in particular application in the aforementioned indications. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNizsKwkAQQNNYiHqHKRUyYNz4axXFXq3DkJ3oQjK77K5BO8_kkTyJKSwsrR483usnPlviOHs_X85bx_KoJ9gZ1Qm0d6Mth-gJc2RBhVYYNHvTUjQtp3ALDPHKnm2VAomGhrUpqWGJUFqJZMTIBQIZ_fMNk15FdeDRl4ME9rvT9oDsbMHBUcnCsTgf11OVr-aLzUz9kXwAKh5Dig</recordid><startdate>20150519</startdate><enddate>20150519</enddate><creator>MENGES FREDERIK</creator><creator>KUHNKE JOACHIM</creator><creator>RING SVEN</creator><creator>FRENZEL THOMAS</creator><creator>PRELLE KATJA</creator><creator>BOHLMANN ROLF</creator><creator>HÜBNER JAN</creator><creator>KLAR ULRICH</creator><creator>MUHN HANS PETER</creator><creator>BORDEN STEFFEN</creator><scope>EVB</scope></search><sort><creationdate>20150519</creationdate><title>17-(1′propenyl)-17-3′-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative</title><author>MENGES FREDERIK ; KUHNKE JOACHIM ; RING SVEN ; FRENZEL THOMAS ; PRELLE KATJA ; BOHLMANN ROLF ; HÜBNER JAN ; KLAR ULRICH ; MUHN HANS PETER ; BORDEN STEFFEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US9034856B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>MENGES FREDERIK</creatorcontrib><creatorcontrib>KUHNKE JOACHIM</creatorcontrib><creatorcontrib>RING SVEN</creatorcontrib><creatorcontrib>FRENZEL THOMAS</creatorcontrib><creatorcontrib>PRELLE KATJA</creatorcontrib><creatorcontrib>BOHLMANN ROLF</creatorcontrib><creatorcontrib>HÜBNER JAN</creatorcontrib><creatorcontrib>KLAR ULRICH</creatorcontrib><creatorcontrib>MUHN HANS PETER</creatorcontrib><creatorcontrib>BORDEN STEFFEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MENGES FREDERIK</au><au>KUHNKE JOACHIM</au><au>RING SVEN</au><au>FRENZEL THOMAS</au><au>PRELLE KATJA</au><au>BOHLMANN ROLF</au><au>HÜBNER JAN</au><au>KLAR ULRICH</au><au>MUHN HANS PETER</au><au>BORDEN STEFFEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>17-(1′propenyl)-17-3′-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative</title><date>2015-05-19</date><risdate>2015</risdate><abstract>The invention relates to 17-(1′-propenyl)-17-3′-oxidoestra-4-en-3-one derivatives with the general chemical formula I, where the residues Z, R4, R6a, R6b, R7, R15, R16a, R16b and R18 have the meanings stated in Claim 1, and their solvates, hydrates and salts, including all stereoisomers of these compounds. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives, and in particular application in the aforementioned indications. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES STEROIDS |
| title | 17-(1′propenyl)-17-3′-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative |
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