Methods of treating cancer by administering EMP2 antibodies

The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections and cancer. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The metho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WADEHRA MADHURI, WU ANNA M, GORDON LYNN K, KELLY KATHY A, SHIMAZAKI KAORI, BRAUN JONATHAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections and cancer. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The methods and compositions target cancers which express or overexpress EMP2 nucleic acids and polypeptides by targeting EMP2.