Transdermal delivery of hormones with low concentration of penetration enhancers

The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state cond...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HUBER PETRA, SCHENK DIRK, LANGGUTH THOMAS, DITTGEN MICHAEL, BRACHT STEFAN
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator HUBER PETRA
SCHENK DIRK
LANGGUTH THOMAS
DITTGEN MICHAEL
BRACHT STEFAN
description The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state conditions without the need of incorporating penetration enhancers or permeation enhancers in the drug-containing layer. Satisfactorily plasma levels of the hormones is also achieved throughout a period of at least 1 week, making the patch applicable for being used in female contraception with the concept of administering the patch ones weekly.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US9005653B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US9005653B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US9005653B23</originalsourceid><addsrcrecordid>eNrjZAgIKUrMK05JLcpNzFFISc3JLEstqlTIT1PIyC_Kzc9LLVYozyzJUMjJL1dIzs9LTs0rKUosyczPAykpSM1LhXFT8zISgdJFxTwMrGmJOcWpvFCam0HBzTXE2UM3tSA_PrW4IDEZpCs-NNjSwMDUzNTYyciYCCUAn5k3_A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Transdermal delivery of hormones with low concentration of penetration enhancers</title><source>esp@cenet</source><creator>HUBER PETRA ; SCHENK DIRK ; LANGGUTH THOMAS ; DITTGEN MICHAEL ; BRACHT STEFAN</creator><creatorcontrib>HUBER PETRA ; SCHENK DIRK ; LANGGUTH THOMAS ; DITTGEN MICHAEL ; BRACHT STEFAN</creatorcontrib><description>The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state conditions without the need of incorporating penetration enhancers or permeation enhancers in the drug-containing layer. Satisfactorily plasma levels of the hormones is also achieved throughout a period of at least 1 week, making the patch applicable for being used in female contraception with the concept of administering the patch ones weekly.</description><language>eng</language><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS ; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; FILTERS IMPLANTABLE INTO BLOOD VESSELS ; FIRST-AID KITS ; FOMENTATION ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROSTHESES ; TREATMENT OR PROTECTION OF EYES OR EARS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150414&amp;DB=EPODOC&amp;CC=US&amp;NR=9005653B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150414&amp;DB=EPODOC&amp;CC=US&amp;NR=9005653B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HUBER PETRA</creatorcontrib><creatorcontrib>SCHENK DIRK</creatorcontrib><creatorcontrib>LANGGUTH THOMAS</creatorcontrib><creatorcontrib>DITTGEN MICHAEL</creatorcontrib><creatorcontrib>BRACHT STEFAN</creatorcontrib><title>Transdermal delivery of hormones with low concentration of penetration enhancers</title><description>The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state conditions without the need of incorporating penetration enhancers or permeation enhancers in the drug-containing layer. Satisfactorily plasma levels of the hormones is also achieved throughout a period of at least 1 week, making the patch applicable for being used in female contraception with the concept of administering the patch ones weekly.</description><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS</subject><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>FILTERS IMPLANTABLE INTO BLOOD VESSELS</subject><subject>FIRST-AID KITS</subject><subject>FOMENTATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><subject>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROSTHESES</subject><subject>TREATMENT OR PROTECTION OF EYES OR EARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAgIKUrMK05JLcpNzFFISc3JLEstqlTIT1PIyC_Kzc9LLVYozyzJUMjJL1dIzs9LTs0rKUosyczPAykpSM1LhXFT8zISgdJFxTwMrGmJOcWpvFCam0HBzTXE2UM3tSA_PrW4IDEZpCs-NNjSwMDUzNTYyciYCCUAn5k3_A</recordid><startdate>20150414</startdate><enddate>20150414</enddate><creator>HUBER PETRA</creator><creator>SCHENK DIRK</creator><creator>LANGGUTH THOMAS</creator><creator>DITTGEN MICHAEL</creator><creator>BRACHT STEFAN</creator><scope>EVB</scope></search><sort><creationdate>20150414</creationdate><title>Transdermal delivery of hormones with low concentration of penetration enhancers</title><author>HUBER PETRA ; SCHENK DIRK ; LANGGUTH THOMAS ; DITTGEN MICHAEL ; BRACHT STEFAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US9005653B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>BANDAGES, DRESSINGS OR ABSORBENT PADS</topic><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROSTHESES</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>HUBER PETRA</creatorcontrib><creatorcontrib>SCHENK DIRK</creatorcontrib><creatorcontrib>LANGGUTH THOMAS</creatorcontrib><creatorcontrib>DITTGEN MICHAEL</creatorcontrib><creatorcontrib>BRACHT STEFAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HUBER PETRA</au><au>SCHENK DIRK</au><au>LANGGUTH THOMAS</au><au>DITTGEN MICHAEL</au><au>BRACHT STEFAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Transdermal delivery of hormones with low concentration of penetration enhancers</title><date>2015-04-14</date><risdate>2015</risdate><abstract>The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state conditions without the need of incorporating penetration enhancers or permeation enhancers in the drug-containing layer. Satisfactorily plasma levels of the hormones is also achieved throughout a period of at least 1 week, making the patch applicable for being used in female contraception with the concept of administering the patch ones weekly.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US9005653B2
source esp@cenet
subjects BANDAGES, DRESSINGS OR ABSORBENT PADS
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROSTHESES
TREATMENT OR PROTECTION OF EYES OR EARS
title Transdermal delivery of hormones with low concentration of penetration enhancers
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T04%3A59%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HUBER%20PETRA&rft.date=2015-04-14&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS9005653B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true