Compound useful for the treatment of degenerative and inflammatory diseases

Novel pyrrazolopyridines according to Formula I, able to inhibit JAK are disclosed, these compounds may be prepared as a pharmaceutical composition, and may be used for the prophylaxis and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, all...

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Hauptverfasser:	MENET CHRISTEL JEANNE MARIE, VATER HUW DAVID, HODGES ALASTAIR JAMES
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	MENET CHRISTEL JEANNE MARIE VATER HUW DAVID HODGES ALASTAIR JAMES
description	Novel pyrrazolopyridines according to Formula I, able to inhibit JAK are disclosed, these compounds may be prepared as a pharmaceutical composition, and may be used for the prophylaxis and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, allergy, inflammatory conditions, autoimmune diseases, proliferative diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.
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HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150310&DB=EPODOC&CC=US&NR=8975406B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150310&DB=EPODOC&CC=US&NR=8975406B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MENET CHRISTEL JEANNE MARIE</creatorcontrib><creatorcontrib>VATER HUW DAVID</creatorcontrib><creatorcontrib>HODGES ALASTAIR JAMES</creatorcontrib><title>Compound useful for the treatment of degenerative and inflammatory diseases</title><description>Novel pyrrazolopyridines according to Formula I, able to inhibit JAK are disclosed, these compounds may be prepared as a pharmaceutical composition, and may be used for the prophylaxis and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, allergy, inflammatory conditions, autoimmune diseases, proliferative diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNzD0KAjEQhuE0FqLeYS4giP-2LopgqdbL4H5ZA0kmJBPB27uFB7B6m4d3bK6NhCQ1dlQLbPVkJZO-QJrBGhCVxFKHHhGZ1b1BPGAXrecQWCV_qHMFXFCmZmTZF8x-nRg6n-7NZY4kLUri5zDR9nHbH3ab9WJ7XK7-IF8w7DXG</recordid><startdate>20150310</startdate><enddate>20150310</enddate><creator>MENET CHRISTEL JEANNE MARIE</creator><creator>VATER HUW DAVID</creator><creator>HODGES ALASTAIR JAMES</creator><scope>EVB</scope></search><sort><creationdate>20150310</creationdate><title>Compound useful for the treatment of degenerative and inflammatory diseases</title><author>MENET CHRISTEL JEANNE MARIE ; 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title	Compound useful for the treatment of degenerative and inflammatory diseases
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