Thiazolopyrimidine modulators as immunosuppressive agents
The present invention relates to compound of formula I, II, III, or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as defined in the claim 1. The present invention also...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | JANG MI-YEON WAER MARK JOZEF ALBERT LOUAT THIERRY ANDRE MICHEL VANDERHOYDONCK BART GAO LING-JIE LIN YUAN HERMAN JEAN FERDINAND HERDEWIJN PIET DE JONGHE STEVEN |
| description | The present invention relates to compound of formula I, II, III, or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as defined in the claim 1. The present invention also relates to a method for their preparation, as well as to pharmaceutical compositions thereof. The present invention further relates to the use of said compounds as biologically active ingredients, more specifically as medicaments for the treatment of disorders and pathologic conditions such as, but not limited to, immune and auto-immune disorders, organ and cells transplant rejections. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US8901132B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US8901132B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US8901132B23</originalsourceid><addsrcrecordid>eNrjZLAMychMrMrPyS-oLMrMzUzJzEtVyM1PKc1JLMkvKlZILFbIzM0tzcsvLi0oKEotLs4sS1VITE_NKynmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxocEWlgaGhsZGTkbGRCgBAJcLL-Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Thiazolopyrimidine modulators as immunosuppressive agents</title><source>esp@cenet</source><creator>JANG MI-YEON ; WAER MARK JOZEF ALBERT ; LOUAT THIERRY ANDRE MICHEL ; VANDERHOYDONCK BART ; GAO LING-JIE ; LIN YUAN ; HERMAN JEAN FERDINAND ; HERDEWIJN PIET ; DE JONGHE STEVEN</creator><creatorcontrib>JANG MI-YEON ; WAER MARK JOZEF ALBERT ; LOUAT THIERRY ANDRE MICHEL ; VANDERHOYDONCK BART ; GAO LING-JIE ; LIN YUAN ; HERMAN JEAN FERDINAND ; HERDEWIJN PIET ; DE JONGHE STEVEN</creatorcontrib><description>The present invention relates to compound of formula I, II, III, or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as defined in the claim 1. The present invention also relates to a method for their preparation, as well as to pharmaceutical compositions thereof. The present invention further relates to the use of said compounds as biologically active ingredients, more specifically as medicaments for the treatment of disorders and pathologic conditions such as, but not limited to, immune and auto-immune disorders, organ and cells transplant rejections.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141202&DB=EPODOC&CC=US&NR=8901132B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141202&DB=EPODOC&CC=US&NR=8901132B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JANG MI-YEON</creatorcontrib><creatorcontrib>WAER MARK JOZEF ALBERT</creatorcontrib><creatorcontrib>LOUAT THIERRY ANDRE MICHEL</creatorcontrib><creatorcontrib>VANDERHOYDONCK BART</creatorcontrib><creatorcontrib>GAO LING-JIE</creatorcontrib><creatorcontrib>LIN YUAN</creatorcontrib><creatorcontrib>HERMAN JEAN FERDINAND</creatorcontrib><creatorcontrib>HERDEWIJN PIET</creatorcontrib><creatorcontrib>DE JONGHE STEVEN</creatorcontrib><title>Thiazolopyrimidine modulators as immunosuppressive agents</title><description>The present invention relates to compound of formula I, II, III, or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as defined in the claim 1. The present invention also relates to a method for their preparation, as well as to pharmaceutical compositions thereof. The present invention further relates to the use of said compounds as biologically active ingredients, more specifically as medicaments for the treatment of disorders and pathologic conditions such as, but not limited to, immune and auto-immune disorders, organ and cells transplant rejections.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAMychMrMrPyS-oLMrMzUzJzEtVyM1PKc1JLMkvKlZILFbIzM0tzcsvLi0oKEotLs4sS1VITE_NKynmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxocEWlgaGhsZGTkbGRCgBAJcLL-Q</recordid><startdate>20141202</startdate><enddate>20141202</enddate><creator>JANG MI-YEON</creator><creator>WAER MARK JOZEF ALBERT</creator><creator>LOUAT THIERRY ANDRE MICHEL</creator><creator>VANDERHOYDONCK BART</creator><creator>GAO LING-JIE</creator><creator>LIN YUAN</creator><creator>HERMAN JEAN FERDINAND</creator><creator>HERDEWIJN PIET</creator><creator>DE JONGHE STEVEN</creator><scope>EVB</scope></search><sort><creationdate>20141202</creationdate><title>Thiazolopyrimidine modulators as immunosuppressive agents</title><author>JANG MI-YEON ; WAER MARK JOZEF ALBERT ; LOUAT THIERRY ANDRE MICHEL ; VANDERHOYDONCK BART ; GAO LING-JIE ; LIN YUAN ; HERMAN JEAN FERDINAND ; HERDEWIJN PIET ; DE JONGHE STEVEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US8901132B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2014</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>JANG MI-YEON</creatorcontrib><creatorcontrib>WAER MARK JOZEF ALBERT</creatorcontrib><creatorcontrib>LOUAT THIERRY ANDRE MICHEL</creatorcontrib><creatorcontrib>VANDERHOYDONCK BART</creatorcontrib><creatorcontrib>GAO LING-JIE</creatorcontrib><creatorcontrib>LIN YUAN</creatorcontrib><creatorcontrib>HERMAN JEAN FERDINAND</creatorcontrib><creatorcontrib>HERDEWIJN PIET</creatorcontrib><creatorcontrib>DE JONGHE STEVEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JANG MI-YEON</au><au>WAER MARK JOZEF ALBERT</au><au>LOUAT THIERRY ANDRE MICHEL</au><au>VANDERHOYDONCK BART</au><au>GAO LING-JIE</au><au>LIN YUAN</au><au>HERMAN JEAN FERDINAND</au><au>HERDEWIJN PIET</au><au>DE JONGHE STEVEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Thiazolopyrimidine modulators as immunosuppressive agents</title><date>2014-12-02</date><risdate>2014</risdate><abstract>The present invention relates to compound of formula I, II, III, or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as defined in the claim 1. The present invention also relates to a method for their preparation, as well as to pharmaceutical compositions thereof. The present invention further relates to the use of said compounds as biologically active ingredients, more specifically as medicaments for the treatment of disorders and pathologic conditions such as, but not limited to, immune and auto-immune disorders, organ and cells transplant rejections.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US8901132B2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Thiazolopyrimidine modulators as immunosuppressive agents |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T20%3A46%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=JANG%20MI-YEON&rft.date=2014-12-02&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS8901132B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |