Triazolopyridine compounds as PIM kinase inhibitors

Triazolopyridine compounds as PIM kinase inhibitors

Provided herein are methods of treating diseases mediated by PIM-1 and/or PIM-2 and/or PIM-3 kinases by administering to a mammal in need thereof a therapeutically effective amount of a compound of Formula I: in which B, R1, R1a, R2, R3, R4, R5, R6, R7, R10 and R11 have the meanings given in the spe...

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Hauptverfasser: HICKEN ERIK JAMES, ROBINSON JOHN E, ALLEN SHELLEY, MUNSON MARK C, LYSSIKATOS JOSEPH P, HICKS JULIE MARIE, ZHAO QIAN, DELISLE ROBERT KIRK, MARMSATER FREDRIK P
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Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator HICKEN ERIK JAMES
ROBINSON JOHN E
ALLEN SHELLEY
MUNSON MARK C
LYSSIKATOS JOSEPH P
HICKS JULIE MARIE
ZHAO QIAN
DELISLE ROBERT KIRK
MARMSATER FREDRIK P
description Provided herein are methods of treating diseases mediated by PIM-1 and/or PIM-2 and/or PIM-3 kinases by administering to a mammal in need thereof a therapeutically effective amount of a compound of Formula I: in which B, R1, R1a, R2, R3, R4, R5, R6, R7, R10 and R11 have the meanings given in the specification.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Triazolopyridine compounds as PIM kinase inhibitors
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