Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors

The present invention provides a compound of formula (I): said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatm...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MCQUIRE LESLIE WIGHTON, WEILER SVEN, ROGEL OLIVIER, TOMMASI RUBEN ALBERTO, SHULTZ MICHAEL
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator MCQUIRE LESLIE WIGHTON
WEILER SVEN
ROGEL OLIVIER
TOMMASI RUBEN ALBERTO
SHULTZ MICHAEL
description The present invention provides a compound of formula (I): said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-12 and/or MMP-13. Finally, the present invention also provides pharmaceutical composition that include the compound of formula (I).
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US8841291B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US8841291B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US8841291B23</originalsourceid><addsrcrecordid>eNrjZLAJTs1JTS7JLEtVyKhMKcqvSMzNTFZITM5MUUhKLE5NUfD1DdA1NFJIzIMyjRUy8zIykzJL8ouKeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJfGiwhYWJoZGloZORMRFKAMHtLaY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors</title><source>esp@cenet</source><creator>MCQUIRE LESLIE WIGHTON ; WEILER SVEN ; ROGEL OLIVIER ; TOMMASI RUBEN ALBERTO ; SHULTZ MICHAEL</creator><creatorcontrib>MCQUIRE LESLIE WIGHTON ; WEILER SVEN ; ROGEL OLIVIER ; TOMMASI RUBEN ALBERTO ; SHULTZ MICHAEL</creatorcontrib><description>The present invention provides a compound of formula (I): said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-12 and/or MMP-13. Finally, the present invention also provides pharmaceutical composition that include the compound of formula (I).</description><language>eng</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; TRAPPING</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20140923&amp;DB=EPODOC&amp;CC=US&amp;NR=8841291B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20140923&amp;DB=EPODOC&amp;CC=US&amp;NR=8841291B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MCQUIRE LESLIE WIGHTON</creatorcontrib><creatorcontrib>WEILER SVEN</creatorcontrib><creatorcontrib>ROGEL OLIVIER</creatorcontrib><creatorcontrib>TOMMASI RUBEN ALBERTO</creatorcontrib><creatorcontrib>SHULTZ MICHAEL</creatorcontrib><title>Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors</title><description>The present invention provides a compound of formula (I): said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-12 and/or MMP-13. Finally, the present invention also provides pharmaceutical composition that include the compound of formula (I).</description><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PEST REPELLANTS OR ATTRACTANTS</subject><subject>PLANT GROWTH REGULATORS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</subject><subject>TRAPPING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAJTs1JTS7JLEtVyKhMKcqvSMzNTFZITM5MUUhKLE5NUfD1DdA1NFJIzIMyjRUy8zIykzJL8ouKeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJfGiwhYWJoZGloZORMRFKAMHtLaY</recordid><startdate>20140923</startdate><enddate>20140923</enddate><creator>MCQUIRE LESLIE WIGHTON</creator><creator>WEILER SVEN</creator><creator>ROGEL OLIVIER</creator><creator>TOMMASI RUBEN ALBERTO</creator><creator>SHULTZ MICHAEL</creator><scope>EVB</scope></search><sort><creationdate>20140923</creationdate><title>Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors</title><author>MCQUIRE LESLIE WIGHTON ; WEILER SVEN ; ROGEL OLIVIER ; TOMMASI RUBEN ALBERTO ; SHULTZ MICHAEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US8841291B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2014</creationdate><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PEST REPELLANTS OR ATTRACTANTS</topic><topic>PLANT GROWTH REGULATORS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</topic><topic>TRAPPING</topic><toplevel>online_resources</toplevel><creatorcontrib>MCQUIRE LESLIE WIGHTON</creatorcontrib><creatorcontrib>WEILER SVEN</creatorcontrib><creatorcontrib>ROGEL OLIVIER</creatorcontrib><creatorcontrib>TOMMASI RUBEN ALBERTO</creatorcontrib><creatorcontrib>SHULTZ MICHAEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MCQUIRE LESLIE WIGHTON</au><au>WEILER SVEN</au><au>ROGEL OLIVIER</au><au>TOMMASI RUBEN ALBERTO</au><au>SHULTZ MICHAEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors</title><date>2014-09-23</date><risdate>2014</risdate><abstract>The present invention provides a compound of formula (I): said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-12 and/or MMP-13. Finally, the present invention also provides pharmaceutical composition that include the compound of formula (I).</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US8841291B2
source esp@cenet
subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
title Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T11%3A31%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=MCQUIRE%20LESLIE%20WIGHTON&rft.date=2014-09-23&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS8841291B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true