Methods for the preparation of drospirenone and intermediates thereof

The invention relates to a process for the preparation of Drospirenone in high yields and purity starting from a compound of formula 2 wherein R is a hydroxyl protective group as defined in the claims, through a sequence of oxidation, deprotection, lactonization and water elimination steps, and wher...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GAMBARIN LUCA, ANDRIOLO ERIKA, MONTORSI MAURO, SCALAPRICE ROMEO, MERLO MASSIMO, ORRU′ GIANMAURO, MARIANI EDOARDO
Format: Patent
Sprache:eng
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