Template fixed beta-hairpin loop mimetics and their use in phage display

A method of screening for template-fixed -hairpin mimetics and libraries including a plurality of these mimetics is provided. The template-fixed -hairpin mimetics are of the following general formula: R1-Cys-Z-Cys-R2  I wherein the two cysteine residues are bridged by a disulfide bond, thereby formi...

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Hauptverfasser: GOMBERT FRANK OTTO, JUNG FRANÇOISE, OBRECHT DANIEL, LOCURIO SERGIO, LUDIN CHRISTIAN, VRIJBLOED JAN WIM
Format: Patent
Sprache:eng
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