Microfluidized oil-in-water emulsions and vaccine compositions

Microfluidized oil-in-water emulsions and vaccine compositions

This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emu...

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Hauptverfasser: KREBS RICHARD L, DOMINOWSKI PAUL J, MANNAN RAMASAMY M, KLOSE PAMELA K
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator KREBS RICHARD L
DOMINOWSKI PAUL J
MANNAN RAMASAMY M
KLOSE PAMELA K
description This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Microfluidized oil-in-water emulsions and vaccine compositions
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