6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asth...
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| creator | ARNOLD LEE D ZHANG TAO CESARIO CARA LAUFER RADOSLAW NIGRO ANTHONY I MULVIHILL MARK J LI AN-HU FOREMAN KENNETH MULVIHILL KRISTEN MICHELLE DONG HANQING WYLE MICHAEL J PANICKER BIJOY HONDA AYAKO COATE HEATHER STEINIG ARNO G SUN YINGCHUAN WERNER DOUGLAS S CREW ANDREW P WENG QUINGHUA |
| description | Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system. |
| format | Patent |
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| subjects | AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING |
| title | 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors |
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