Bonding tissues and cross-linking proteins with naphthalimide compounds
Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together,...
Gespeichert in:
Hauptverfasser: | , , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | UTECHT RONALD E VASKA KEVIN J JUDY MILLARD M MATTHEWS JAMES L KLOSTER KAIA L |
description | Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bond tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues without subsequent direct illumination of the contacted tissue area. The naphthalimide compounds may be used in tissue or arterial repair, stabilization of an expanded arterial wall after angioplasty, tethering pharmaceutical agents to tissue surfaces to provide local drug delivery, and for chemically bonding skin care products, sunscreens, and cosmetics to the skin. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US8632565B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US8632565B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US8632565B23</originalsourceid><addsrcrecordid>eNqNyjEOwjAMQNEsDKhwB1-gS6tWzEVAd2CuosQQi9S26lRcHyFxAKY_vL91l0E4Ej-hkNmKBp4jhEXM6kz8-oouUpDY4E0lAXtNJflMM0WEILPKytF2bvPw2XD_a-XgfLodxxpVJjT1ARnLdL8e-rbp-m5o2j-WD2AjNI0</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Bonding tissues and cross-linking proteins with naphthalimide compounds</title><source>esp@cenet</source><creator>UTECHT RONALD E ; VASKA KEVIN J ; JUDY MILLARD M ; MATTHEWS JAMES L ; KLOSTER KAIA L</creator><creatorcontrib>UTECHT RONALD E ; VASKA KEVIN J ; JUDY MILLARD M ; MATTHEWS JAMES L ; KLOSTER KAIA L</creatorcontrib><description>Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bond tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues without subsequent direct illumination of the contacted tissue area. The naphthalimide compounds may be used in tissue or arterial repair, stabilization of an expanded arterial wall after angioplasty, tethering pharmaceutical agents to tissue surfaces to provide local drug delivery, and for chemically bonding skin care products, sunscreens, and cosmetics to the skin.</description><language>eng</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; CHEMISTRY ; COMPOSITIONS BASED THEREON ; DERIVATIVES THEREOF ; DIAGNOSIS ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; HYGIENE ; IDENTIFICATION ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; ORGANIC MACROMOLECULAR COMPOUNDS ; PEPTIDES ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; POLYSACCHARIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; SURGERY ; THEIR PREPARATION OR CHEMICAL WORKING-UP ; TRAPPING ; VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140121&DB=EPODOC&CC=US&NR=8632565B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140121&DB=EPODOC&CC=US&NR=8632565B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>UTECHT RONALD E</creatorcontrib><creatorcontrib>VASKA KEVIN J</creatorcontrib><creatorcontrib>JUDY MILLARD M</creatorcontrib><creatorcontrib>MATTHEWS JAMES L</creatorcontrib><creatorcontrib>KLOSTER KAIA L</creatorcontrib><title>Bonding tissues and cross-linking proteins with naphthalimide compounds</title><description>Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bond tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues without subsequent direct illumination of the contacted tissue area. The naphthalimide compounds may be used in tissue or arterial repair, stabilization of an expanded arterial wall after angioplasty, tethering pharmaceutical agents to tissue surfaces to provide local drug delivery, and for chemically bonding skin care products, sunscreens, and cosmetics to the skin.</description><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>DERIVATIVES THEREOF</subject><subject>DIAGNOSIS</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>HYGIENE</subject><subject>IDENTIFICATION</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>PEPTIDES</subject><subject>PEST REPELLANTS OR ATTRACTANTS</subject><subject>PLANT GROWTH REGULATORS</subject><subject>POLYSACCHARIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</subject><subject>SURGERY</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><subject>TRAPPING</subject><subject>VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyjEOwjAMQNEsDKhwB1-gS6tWzEVAd2CuosQQi9S26lRcHyFxAKY_vL91l0E4Ej-hkNmKBp4jhEXM6kz8-oouUpDY4E0lAXtNJflMM0WEILPKytF2bvPw2XD_a-XgfLodxxpVJjT1ARnLdL8e-rbp-m5o2j-WD2AjNI0</recordid><startdate>20140121</startdate><enddate>20140121</enddate><creator>UTECHT RONALD E</creator><creator>VASKA KEVIN J</creator><creator>JUDY MILLARD M</creator><creator>MATTHEWS JAMES L</creator><creator>KLOSTER KAIA L</creator><scope>EVB</scope></search><sort><creationdate>20140121</creationdate><title>Bonding tissues and cross-linking proteins with naphthalimide compounds</title><author>UTECHT RONALD E ; VASKA KEVIN J ; JUDY MILLARD M ; MATTHEWS JAMES L ; KLOSTER KAIA L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US8632565B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2014</creationdate><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>DERIVATIVES THEREOF</topic><topic>DIAGNOSIS</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>HYGIENE</topic><topic>IDENTIFICATION</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>PEPTIDES</topic><topic>PEST REPELLANTS OR ATTRACTANTS</topic><topic>PLANT GROWTH REGULATORS</topic><topic>POLYSACCHARIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</topic><topic>SURGERY</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><topic>TRAPPING</topic><topic>VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS</topic><toplevel>online_resources</toplevel><creatorcontrib>UTECHT RONALD E</creatorcontrib><creatorcontrib>VASKA KEVIN J</creatorcontrib><creatorcontrib>JUDY MILLARD M</creatorcontrib><creatorcontrib>MATTHEWS JAMES L</creatorcontrib><creatorcontrib>KLOSTER KAIA L</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>UTECHT RONALD E</au><au>VASKA KEVIN J</au><au>JUDY MILLARD M</au><au>MATTHEWS JAMES L</au><au>KLOSTER KAIA L</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Bonding tissues and cross-linking proteins with naphthalimide compounds</title><date>2014-01-21</date><risdate>2014</risdate><abstract>Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bond tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues without subsequent direct illumination of the contacted tissue area. The naphthalimide compounds may be used in tissue or arterial repair, stabilization of an expanded arterial wall after angioplasty, tethering pharmaceutical agents to tissue surfaces to provide local drug delivery, and for chemically bonding skin care products, sunscreens, and cosmetics to the skin.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_epo_espacenet_US8632565B2 |
source | esp@cenet |
subjects | AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF DIAGNOSIS FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE IDENTIFICATION MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PEPTIDES PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF SURGERY THEIR PREPARATION OR CHEMICAL WORKING-UP TRAPPING VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS |
title | Bonding tissues and cross-linking proteins with naphthalimide compounds |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T11%3A46%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=UTECHT%20RONALD%20E&rft.date=2014-01-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS8632565B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |