Heterocyclic amides as modulators of TRPA1

Certain heterocyclic amide compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPA1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease.

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Hauptverfasser: BERTHELOT DIDIER JEAN-CALUDE, RECH JASON, LEBSACK ALEC, GIJSEN HENRICUS JACOBUS MARIA, XIAO WEI, BREITENBUCHER J. GUY, ZAJA MIRKO, BRANSTETTER BRYAN
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creator BERTHELOT DIDIER JEAN-CALUDE
RECH JASON
LEBSACK ALEC
GIJSEN HENRICUS JACOBUS MARIA
XIAO WEI
BREITENBUCHER J. GUY
ZAJA MIRKO
BRANSTETTER BRYAN
description Certain heterocyclic amide compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPA1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMISTRY
FISHING
FORESTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
title Heterocyclic amides as modulators of TRPA1
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