Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma

The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms and wherein R is Cl and wherein R may be located either in the para-, meta- or ortho-position of Ring A, whe...

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Hauptverfasser: MULDER JASON ALAN, SANANAYAKE CHRIS HUGH, FRUTOS ROGELIO PEREZ, NICKOLAUS PETER, KIM SOOJIN, TAMPONE THOMAS GABRIEL, YANG BING-SHIOU, PATEL NITINCHANDRA D, WEI XUDONG, WERTHMANN ULRIKE, POUZET PASCALE A. J
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creator MULDER JASON ALAN
SANANAYAKE CHRIS HUGH
FRUTOS ROGELIO PEREZ
NICKOLAUS PETER
KIM SOOJIN
TAMPONE THOMAS GABRIEL
YANG BING-SHIOU
PATEL NITINCHANDRA D
WEI XUDONG
WERTHMANN ULRIKE
POUZET PASCALE A. J
description The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms and wherein R is Cl and wherein R may be located either in the para-, meta- or ortho-position of Ring A, wherein S* is a sulphur atom that represents a chiral center, and all pharmaceutically acceptable salts, enantiomers and racemates, hydrates and solvates thereof and the use of these compounds for the treatment of inflammatory or allergic diseases of the respiratory tract such as COPD or asthma.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
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