Furo[3,2-d]pyrimidine compounds

Furo[3,2-d]pyrimidine compounds

The present invention is directed to novel compounds of Formula (I) pharmaceutically acceptable salts, biologically active metabolites, pro-drugs, racemates, enantiomers, diastereomers, solvates and hydrates thereof wherein the variables are defined as herein. The compounds of Formula (I) are useful...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CLAPHAM BRUCE, VILLAMIL CLARA I, WILSON NOEL S, HOEMANN MICHAEL Z, VASUDEVAN ANIL, SOMAL GAGANDEEP, LI BIN, CALDERWOOD DAVID J, MULLEN KELLY D, COX PHILIP
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention is directed to novel compounds of Formula (I) pharmaceutically acceptable salts, biologically active metabolites, pro-drugs, racemates, enantiomers, diastereomers, solvates and hydrates thereof wherein the variables are defined as herein. The compounds of Formula (I) are useful as kinase inhibitors and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers.