Crystalline composition of GM-CSF/GM-CSFR

The present invention relates generally to the field of crystallography. More particularly, the present invention provides crystalline forms of a complex between granulocyte macrophage-colony stimulating factor (GM-CSF) and its receptor (GM-CSFR). The present invention further provides methods for t...

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Hauptverfasser: HERCUS TIMOTHY ROBERT, PARKER MICHAEL WILLIAM, HANSEN GUIDO, LOPEZ ANGEL FRANCISCO, MCKINSTRY WILLIAM JOHN
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creator HERCUS TIMOTHY ROBERT
PARKER MICHAEL WILLIAM
HANSEN GUIDO
LOPEZ ANGEL FRANCISCO
MCKINSTRY WILLIAM JOHN
description The present invention relates generally to the field of crystallography. More particularly, the present invention provides crystalline forms of a complex between granulocyte macrophage-colony stimulating factor (GM-CSF) and its receptor (GM-CSFR). The present invention further provides methods for the design and selection of modulators of GM-CSF/GM-CSFR interaction and signaling as well as signaling of other cytokines.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title Crystalline composition of GM-CSF/GM-CSFR
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