Assay for evaluating affinity and specificity of ligand-albumin binding

A method for identifying a ligand or compound which binds to albumin comprises the steps of contacting a reaction mixture comprising a site-specific probe and albumin in the presence and the absence of the ligand or compound and measuring either dissociation constant KD, inhibitor concentration IC50...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	KRANZ JAMES K, TODD GABRIELLE C, TODD MATTHEW J
Format:	Patent
Sprache:	eng
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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