Pyrrolotriazines as ALK and JAK2 inhibitors

The present invention provides a compound of formula I or a salt form thereof, wherein Q1, Q2, Q3, and Q4 are as defined herein. The compound of formula I has ALK and/or JAK2 inhibitory activity, and may be used to treat proliferative disorders.

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Bibliographische Detailangaben
Hauptverfasser:	GINGRICH DIANE E, UNDERINER THEODORE L, JOSEF KURT A, MESAROS EUGEN F, OTT GREGORY R, HOSTETLER GREG A, LISKO JOSEPH, DORSEY BRUCE D, DUNN DEREK D, TRIPATHY RABINDRANATH, SUNDAR BABU G, WEINBERG LINDA, WELLS GREGORY J, ZIFICSAK CRAIG A, MILKIEWICZ KAREN L, BRESLIN HENRY J, THEROFF JAY P, CHATTERJEE SANKAR, HUNTER RACHAEL, DIEBOLD JAMES L, HUDKINS ROBERT L, THIEU THO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula I or a salt form thereof, wherein Q1, Q2, Q3, and Q4 are as defined herein. The compound of formula I has ALK and/or JAK2 inhibitory activity, and may be used to treat proliferative disorders.