Composition exhibiting enhanced formulation stability and delivery of topical active ingredients

A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. T...

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Hauptverfasser: GANS ORIT, SERI-LEVY ALON, AVNIR DAVID, LAPIDOT NOA, MAGDASSI SHLOMO, ROTTMAN CLAUDI
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creator GANS ORIT
SERI-LEVY ALON
AVNIR DAVID
LAPIDOT NOA
MAGDASSI SHLOMO
ROTTMAN CLAUDI
description A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
title Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
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