Method for diagnosing cancers expressing the HER2 receptor or its truncated variants

The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognizes an epitope of a HER2 receptor truncated form, said epitope being defined by a sequence included in SEQ ID NO: 2. The inve...

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Hauptverfasser: TORRES JOSE BASELGA, PALAU JOSEP LIUIS PARRA, LOPEZ JOAQUIN ARRIBAS, ANGELLINI PIER-DAVIDE, PEDERSEN KIM, LAOS SIRLE
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creator TORRES JOSE BASELGA
PALAU JOSEP LIUIS PARRA
LOPEZ JOAQUIN ARRIBAS
ANGELLINI PIER-DAVIDE
PEDERSEN KIM
LAOS SIRLE
description The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognizes an epitope of a HER2 receptor truncated form, said epitope being defined by a sequence included in SEQ ID NO: 2. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ ID NO: 1 in a patient sample.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
SPIRITS
TESTING
VINEGAR
WINE
title Method for diagnosing cancers expressing the HER2 receptor or its truncated variants
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