Process for pure duloxetine hydrochloride

A process for the preparation of pure Duloxetine hydrochloride comprises the steps of: a) reacting 1-(thiophen-2-yl)ethanone with dimethylamine hydrochloride, b) purifying the component in a solvent, c) reducing the component with an alkali metal borohydride, d) resolving the compound with a chiral...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RAJAN SRINIVASAN THIRUMALAI, PRASAD DURGADAS SHYLA, REDDY MANNE SATYANARAYANA, KUMAR MUPPA KISHORE
Format: Patent
Sprache:eng
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