N-containing heterocyclic compounds

The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: FEUTRILL JOHN THOMAS, CUZZUPE ANTHONY NICHOLAS, BOURKE DAVID GERARD, NERO TRACY LEAH, BURNS CHRISTOPHER JOHN, KLING MARCEL ROBERT
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator FEUTRILL JOHN THOMAS
CUZZUPE ANTHONY NICHOLAS
BOURKE DAVID GERARD
NERO TRACY LEAH
BURNS CHRISTOPHER JOHN
KLING MARCEL ROBERT
description The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US8354408B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US8354408B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US8354408B23</originalsourceid><addsrcrecordid>eNrjZFD2003OzytJzMzLzEtXyEgtSS3KT65MzslMVkjOzy3IL81LKeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfGhwRbGpiYmBhZORsZEKAEAvtUmlw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>N-containing heterocyclic compounds</title><source>esp@cenet</source><creator>FEUTRILL JOHN THOMAS ; CUZZUPE ANTHONY NICHOLAS ; BOURKE DAVID GERARD ; NERO TRACY LEAH ; BURNS CHRISTOPHER JOHN ; KLING MARCEL ROBERT</creator><creatorcontrib>FEUTRILL JOHN THOMAS ; CUZZUPE ANTHONY NICHOLAS ; BOURKE DAVID GERARD ; NERO TRACY LEAH ; BURNS CHRISTOPHER JOHN ; KLING MARCEL ROBERT</creatorcontrib><description>The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130115&amp;DB=EPODOC&amp;CC=US&amp;NR=8354408B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130115&amp;DB=EPODOC&amp;CC=US&amp;NR=8354408B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FEUTRILL JOHN THOMAS</creatorcontrib><creatorcontrib>CUZZUPE ANTHONY NICHOLAS</creatorcontrib><creatorcontrib>BOURKE DAVID GERARD</creatorcontrib><creatorcontrib>NERO TRACY LEAH</creatorcontrib><creatorcontrib>BURNS CHRISTOPHER JOHN</creatorcontrib><creatorcontrib>KLING MARCEL ROBERT</creatorcontrib><title>N-containing heterocyclic compounds</title><description>The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFD2003OzytJzMzLzEtXyEgtSS3KT65MzslMVkjOzy3IL81LKeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfGhwRbGpiYmBhZORsZEKAEAvtUmlw</recordid><startdate>20130115</startdate><enddate>20130115</enddate><creator>FEUTRILL JOHN THOMAS</creator><creator>CUZZUPE ANTHONY NICHOLAS</creator><creator>BOURKE DAVID GERARD</creator><creator>NERO TRACY LEAH</creator><creator>BURNS CHRISTOPHER JOHN</creator><creator>KLING MARCEL ROBERT</creator><scope>EVB</scope></search><sort><creationdate>20130115</creationdate><title>N-containing heterocyclic compounds</title><author>FEUTRILL JOHN THOMAS ; CUZZUPE ANTHONY NICHOLAS ; BOURKE DAVID GERARD ; NERO TRACY LEAH ; BURNS CHRISTOPHER JOHN ; KLING MARCEL ROBERT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US8354408B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2013</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>FEUTRILL JOHN THOMAS</creatorcontrib><creatorcontrib>CUZZUPE ANTHONY NICHOLAS</creatorcontrib><creatorcontrib>BOURKE DAVID GERARD</creatorcontrib><creatorcontrib>NERO TRACY LEAH</creatorcontrib><creatorcontrib>BURNS CHRISTOPHER JOHN</creatorcontrib><creatorcontrib>KLING MARCEL ROBERT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FEUTRILL JOHN THOMAS</au><au>CUZZUPE ANTHONY NICHOLAS</au><au>BOURKE DAVID GERARD</au><au>NERO TRACY LEAH</au><au>BURNS CHRISTOPHER JOHN</au><au>KLING MARCEL ROBERT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>N-containing heterocyclic compounds</title><date>2013-01-15</date><risdate>2013</risdate><abstract>The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US8354408B2
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title N-containing heterocyclic compounds
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T10%3A15%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=FEUTRILL%20JOHN%20THOMAS&rft.date=2013-01-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS8354408B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true