N-containing heterocyclic compounds
The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the...
Gespeichert in:
Hauptverfasser: | , , , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | FEUTRILL JOHN THOMAS CUZZUPE ANTHONY NICHOLAS BOURKE DAVID GERARD NERO TRACY LEAH BURNS CHRISTOPHER JOHN KLING MARCEL ROBERT |
description | The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US8354408B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US8354408B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US8354408B23</originalsourceid><addsrcrecordid>eNrjZFD2003OzytJzMzLzEtXyEgtSS3KT65MzslMVkjOzy3IL81LKeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfGhwRbGpiYmBhZORsZEKAEAvtUmlw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>N-containing heterocyclic compounds</title><source>esp@cenet</source><creator>FEUTRILL JOHN THOMAS ; CUZZUPE ANTHONY NICHOLAS ; BOURKE DAVID GERARD ; NERO TRACY LEAH ; BURNS CHRISTOPHER JOHN ; KLING MARCEL ROBERT</creator><creatorcontrib>FEUTRILL JOHN THOMAS ; CUZZUPE ANTHONY NICHOLAS ; BOURKE DAVID GERARD ; NERO TRACY LEAH ; BURNS CHRISTOPHER JOHN ; KLING MARCEL ROBERT</creatorcontrib><description>The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130115&DB=EPODOC&CC=US&NR=8354408B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130115&DB=EPODOC&CC=US&NR=8354408B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FEUTRILL JOHN THOMAS</creatorcontrib><creatorcontrib>CUZZUPE ANTHONY NICHOLAS</creatorcontrib><creatorcontrib>BOURKE DAVID GERARD</creatorcontrib><creatorcontrib>NERO TRACY LEAH</creatorcontrib><creatorcontrib>BURNS CHRISTOPHER JOHN</creatorcontrib><creatorcontrib>KLING MARCEL ROBERT</creatorcontrib><title>N-containing heterocyclic compounds</title><description>The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFD2003OzytJzMzLzEtXyEgtSS3KT65MzslMVkjOzy3IL81LKeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfGhwRbGpiYmBhZORsZEKAEAvtUmlw</recordid><startdate>20130115</startdate><enddate>20130115</enddate><creator>FEUTRILL JOHN THOMAS</creator><creator>CUZZUPE ANTHONY NICHOLAS</creator><creator>BOURKE DAVID GERARD</creator><creator>NERO TRACY LEAH</creator><creator>BURNS CHRISTOPHER JOHN</creator><creator>KLING MARCEL ROBERT</creator><scope>EVB</scope></search><sort><creationdate>20130115</creationdate><title>N-containing heterocyclic compounds</title><author>FEUTRILL JOHN THOMAS ; CUZZUPE ANTHONY NICHOLAS ; BOURKE DAVID GERARD ; NERO TRACY LEAH ; BURNS CHRISTOPHER JOHN ; KLING MARCEL ROBERT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US8354408B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2013</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>FEUTRILL JOHN THOMAS</creatorcontrib><creatorcontrib>CUZZUPE ANTHONY NICHOLAS</creatorcontrib><creatorcontrib>BOURKE DAVID GERARD</creatorcontrib><creatorcontrib>NERO TRACY LEAH</creatorcontrib><creatorcontrib>BURNS CHRISTOPHER JOHN</creatorcontrib><creatorcontrib>KLING MARCEL ROBERT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FEUTRILL JOHN THOMAS</au><au>CUZZUPE ANTHONY NICHOLAS</au><au>BOURKE DAVID GERARD</au><au>NERO TRACY LEAH</au><au>BURNS CHRISTOPHER JOHN</au><au>KLING MARCEL ROBERT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>N-containing heterocyclic compounds</title><date>2013-01-15</date><risdate>2013</risdate><abstract>The present invention relates to N-containing heterocyclic compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2, JAK3 or TYK2 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_epo_espacenet_US8354408B2 |
source | esp@cenet |
subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | N-containing heterocyclic compounds |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T10%3A15%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=FEUTRILL%20JOHN%20THOMAS&rft.date=2013-01-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS8354408B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |