Peripheral opioid receptor antagonists and uses thereof

Peripheral opioid receptor antagonists and uses thereof

The present invention provides a compound of formula I: wherein X−, R1, and R2 are as defined herein, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LOKHNAUTH JOHN, MELUCCI CHARLES K
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator LOKHNAUTH JOHN
MELUCCI CHARLES K
description The present invention provides a compound of formula I: wherein X−, R1, and R2 are as defined herein, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US8338446B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US8338446B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US8338446B23</originalsourceid><addsrcrecordid>eNrjZDAPSC3KLMhILUrMUcgvyMzPTFEoSk1OLSjJL1JIzCtJTM_PyywuKQayUxRKi1OLFUqAalPz03gYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxQWJyal5qSXxosIWxsYWJiZmTkTERSgC3YC43</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Peripheral opioid receptor antagonists and uses thereof</title><source>esp@cenet</source><creator>LOKHNAUTH JOHN ; MELUCCI CHARLES K</creator><creatorcontrib>LOKHNAUTH JOHN ; MELUCCI CHARLES K</creatorcontrib><description>The present invention provides a compound of formula I: wherein X−, R1, and R2 are as defined herein, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20121225&amp;DB=EPODOC&amp;CC=US&amp;NR=8338446B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20121225&amp;DB=EPODOC&amp;CC=US&amp;NR=8338446B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LOKHNAUTH JOHN</creatorcontrib><creatorcontrib>MELUCCI CHARLES K</creatorcontrib><title>Peripheral opioid receptor antagonists and uses thereof</title><description>The present invention provides a compound of formula I: wherein X−, R1, and R2 are as defined herein, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAPSC3KLMhILUrMUcgvyMzPTFEoSk1OLSjJL1JIzCtJTM_PyywuKQayUxRKi1OLFUqAalPz03gYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxQWJyal5qSXxosIWxsYWJiZmTkTERSgC3YC43</recordid><startdate>20121225</startdate><enddate>20121225</enddate><creator>LOKHNAUTH JOHN</creator><creator>MELUCCI CHARLES K</creator><scope>EVB</scope></search><sort><creationdate>20121225</creationdate><title>Peripheral opioid receptor antagonists and uses thereof</title><author>LOKHNAUTH JOHN ; MELUCCI CHARLES K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US8338446B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LOKHNAUTH JOHN</creatorcontrib><creatorcontrib>MELUCCI CHARLES K</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LOKHNAUTH JOHN</au><au>MELUCCI CHARLES K</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Peripheral opioid receptor antagonists and uses thereof</title><date>2012-12-25</date><risdate>2012</risdate><abstract>The present invention provides a compound of formula I: wherein X−, R1, and R2 are as defined herein, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US8338446B2
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Peripheral opioid receptor antagonists and uses thereof
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T16%3A06%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LOKHNAUTH%20JOHN&rft.date=2012-12-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS8338446B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true