Organic compounds

The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparatio...

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Hauptverfasser: JACOBY EDGAR, MARZINZIK ANDREAS, ERHARDT CLAUS, BREITENSTEIN WERNER, KAWAKAMI SHIMPEI, OSTERMANN NILS, KONISHI KAZUHIDE, YOKOKAWA FUMIAKI, KANAZAWA TAKANORI, GROSCHE PHILIPP, MAIBAUM JUERGEN KLAUS, MASUYA KEIICHI, ZIMMERMANN JUERG
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creator JACOBY EDGAR
MARZINZIK ANDREAS
ERHARDT CLAUS
BREITENSTEIN WERNER
KAWAKAMI SHIMPEI
OSTERMANN NILS
KONISHI KAZUHIDE
YOKOKAWA FUMIAKI
KANAZAWA TAKANORI
GROSCHE PHILIPP
MAIBAUM JUERGEN KLAUS
MASUYA KEIICHI
ZIMMERMANN JUERG
description The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The preferred compounds (which can also be present as salts) have the formula I wherein R1, R2, T, R3 and R4 are as defined in the specification.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Organic compounds
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