Gene silencing

The present invention relates to unique strategies and constructs for producing a nucleic acid product that down-regulates or prevents expression of a desired target polynucleotide. Such construct may include an expressing cassette having two convergently-oriented promoters each operably linked to a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	ROMMENS CAIUS, BOUGRI OLEG, SWORDS KATHY M. M, YAN HUA
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FISHING FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J FORESTRY HUMAN NECESSITIES HUNTING INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLICBEVERAGES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW PLANTS OR PROCESSES FOR OBTAINING THEM NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to unique strategies and constructs for producing a nucleic acid product that down-regulates or prevents expression of a desired target polynucleotide. Such construct may include an expressing cassette having two convergently-oriented promoters each operably linked to a polynucleotide, but not to a terminator. The two polynucleotides are fully identical in sequence over at least 23 nucleotides.