MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use
Human MAPK genes are identified as modulators of the Rac, axin, and beta-catenin pathways, and thus are therapeutic targets for disorders associated with defective Rac, axin, and beta-catenin function. Methods for identifying modulators of Rac, axin, and beta-catenin, comprising screening for agents...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | FRANCIS GEORGE ROSS LICKTEIG KIM GENDREAU STEVEN BRIAN COSTA MICHAEL R DORA, III EMERY G KADYK LISA C |
| description | Human MAPK genes are identified as modulators of the Rac, axin, and beta-catenin pathways, and thus are therapeutic targets for disorders associated with defective Rac, axin, and beta-catenin function. Methods for identifying modulators of Rac, axin, and beta-catenin, comprising screening for agents that modulate the activity of MAPK are provided. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US8067180B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US8067180B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US8067180B23</originalsourceid><addsrcrecordid>eNrjZAj0dQzwLlZILFbIzU_JTMtMLSpWyE9TKMlIVShKTNZRSKzIzAOSeSkKSaklibrJiSWpeZl5CgWJJRnliZXFYJnc1JKM_BSwvtLiVB4G1rTEnOJUXijNzaDg5hri7KGbWpAfn1pckJicmpdaEh8abGFgZm5oYeBkZEyEEgB_FzXE</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use</title><source>esp@cenet</source><creator>FRANCIS GEORGE ROSS ; LICKTEIG KIM ; GENDREAU STEVEN BRIAN ; COSTA MICHAEL R ; DORA, III EMERY G ; KADYK LISA C</creator><creatorcontrib>FRANCIS GEORGE ROSS ; LICKTEIG KIM ; GENDREAU STEVEN BRIAN ; COSTA MICHAEL R ; DORA, III EMERY G ; KADYK LISA C</creatorcontrib><description>Human MAPK genes are identified as modulators of the Rac, axin, and beta-catenin pathways, and thus are therapeutic targets for disorders associated with defective Rac, axin, and beta-catenin function. Methods for identifying modulators of Rac, axin, and beta-catenin, comprising screening for agents that modulate the activity of MAPK are provided.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111129&DB=EPODOC&CC=US&NR=8067180B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111129&DB=EPODOC&CC=US&NR=8067180B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FRANCIS GEORGE ROSS</creatorcontrib><creatorcontrib>LICKTEIG KIM</creatorcontrib><creatorcontrib>GENDREAU STEVEN BRIAN</creatorcontrib><creatorcontrib>COSTA MICHAEL R</creatorcontrib><creatorcontrib>DORA, III EMERY G</creatorcontrib><creatorcontrib>KADYK LISA C</creatorcontrib><title>MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use</title><description>Human MAPK genes are identified as modulators of the Rac, axin, and beta-catenin pathways, and thus are therapeutic targets for disorders associated with defective Rac, axin, and beta-catenin function. Methods for identifying modulators of Rac, axin, and beta-catenin, comprising screening for agents that modulate the activity of MAPK are provided.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAj0dQzwLlZILFbIzU_JTMtMLSpWyE9TKMlIVShKTNZRSKzIzAOSeSkKSaklibrJiSWpeZl5CgWJJRnliZXFYJnc1JKM_BSwvtLiVB4G1rTEnOJUXijNzaDg5hri7KGbWpAfn1pckJicmpdaEh8abGFgZm5oYeBkZEyEEgB_FzXE</recordid><startdate>20111129</startdate><enddate>20111129</enddate><creator>FRANCIS GEORGE ROSS</creator><creator>LICKTEIG KIM</creator><creator>GENDREAU STEVEN BRIAN</creator><creator>COSTA MICHAEL R</creator><creator>DORA, III EMERY G</creator><creator>KADYK LISA C</creator><scope>EVB</scope></search><sort><creationdate>20111129</creationdate><title>MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use</title><author>FRANCIS GEORGE ROSS ; LICKTEIG KIM ; GENDREAU STEVEN BRIAN ; COSTA MICHAEL R ; DORA, III EMERY G ; KADYK LISA C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US8067180B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2011</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>FRANCIS GEORGE ROSS</creatorcontrib><creatorcontrib>LICKTEIG KIM</creatorcontrib><creatorcontrib>GENDREAU STEVEN BRIAN</creatorcontrib><creatorcontrib>COSTA MICHAEL R</creatorcontrib><creatorcontrib>DORA, III EMERY G</creatorcontrib><creatorcontrib>KADYK LISA C</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FRANCIS GEORGE ROSS</au><au>LICKTEIG KIM</au><au>GENDREAU STEVEN BRIAN</au><au>COSTA MICHAEL R</au><au>DORA, III EMERY G</au><au>KADYK LISA C</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use</title><date>2011-11-29</date><risdate>2011</risdate><abstract>Human MAPK genes are identified as modulators of the Rac, axin, and beta-catenin pathways, and thus are therapeutic targets for disorders associated with defective Rac, axin, and beta-catenin function. Methods for identifying modulators of Rac, axin, and beta-catenin, comprising screening for agents that modulate the activity of MAPK are provided.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US8067180B2 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE |
| title | MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T12%3A45%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=FRANCIS%20GEORGE%20ROSS&rft.date=2011-11-29&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS8067180B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |