Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors

Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors

Nanoparticulate compositions comprising at least one poorly soluble MAP kinase inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such composi...

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Hauptverfasser: KLINE LAURA J, CARY GRETA G, OSTRANDER KEVIN D, JAIN RAJEEV A, RYDE NIELS P, HOVEY DOUGLAS C, MERISKO-LIVERSIDGE ELAINE, BOSCH H. WILLIAM, RUDDY STEPHEN B
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator KLINE LAURA J
CARY GRETA G
OSTRANDER KEVIN D
JAIN RAJEEV A
RYDE NIELS P
HOVEY DOUGLAS C
MERISKO-LIVERSIDGE ELAINE
BOSCH H. WILLIAM
RUDDY STEPHEN B
description Nanoparticulate compositions comprising at least one poorly soluble MAP kinase inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors
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