Non-nucleotide composition for inhibiting platelet aggregation
This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising a...
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creator | TU CHI ALFARO-LOPEZ LORENZO J SHAVER SAMMY R HARVEY DANIEL F WATSON PAUL S BOYER JOSE L ABREO MELWYN A FENG YANGBO PLOURDE, JR. ROBERT KHASONOVA TATYANA V DOUGLASS, III JAMES G |
description | This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a non-nucleotide compound, preferably a P2Y12 receptor antagonist compound, wherein said amount is effective to inhibit platelet aggregation. The compounds useful for this invention include compounds of general Formulae I and III-XII, or salts, hydrates, and solvates thereof. The present invention also provides novel compounds of Formulae I and III-XII. |
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The present invention also provides novel compounds of Formulae I and III-XII.</description><language>eng</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; CHEMISTRY ; DERIVATIVES THEREOF ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; SUGARS ; TRAPPING</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110517&DB=EPODOC&CC=US&NR=7943760B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110517&DB=EPODOC&CC=US&NR=7943760B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TU CHI</creatorcontrib><creatorcontrib>ALFARO-LOPEZ LORENZO J</creatorcontrib><creatorcontrib>SHAVER SAMMY R</creatorcontrib><creatorcontrib>HARVEY DANIEL F</creatorcontrib><creatorcontrib>WATSON PAUL S</creatorcontrib><creatorcontrib>BOYER JOSE L</creatorcontrib><creatorcontrib>ABREO MELWYN A</creatorcontrib><creatorcontrib>FENG YANGBO</creatorcontrib><creatorcontrib>PLOURDE, JR. 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ROBERT</creatorcontrib><creatorcontrib>KHASONOVA TATYANA V</creatorcontrib><creatorcontrib>DOUGLASS, III JAMES G</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TU CHI</au><au>ALFARO-LOPEZ LORENZO J</au><au>SHAVER SAMMY R</au><au>HARVEY DANIEL F</au><au>WATSON PAUL S</au><au>BOYER JOSE L</au><au>ABREO MELWYN A</au><au>FENG YANGBO</au><au>PLOURDE, JR. ROBERT</au><au>KHASONOVA TATYANA V</au><au>DOUGLASS, III JAMES G</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Non-nucleotide composition for inhibiting platelet aggregation</title><date>2011-05-17</date><risdate>2011</risdate><abstract>This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a non-nucleotide compound, preferably a P2Y12 receptor antagonist compound, wherein said amount is effective to inhibit platelet aggregation. The compounds useful for this invention include compounds of general Formulae I and III-XII, or salts, hydrates, and solvates thereof. The present invention also provides novel compounds of Formulae I and III-XII.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY DERIVATIVES THEREOF FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF SUGARS TRAPPING |
title | Non-nucleotide composition for inhibiting platelet aggregation |
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