Non-nucleotide composition for inhibiting platelet aggregation

This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising a...

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Hauptverfasser: TU CHI, ALFARO-LOPEZ LORENZO J, SHAVER SAMMY R, HARVEY DANIEL F, WATSON PAUL S, BOYER JOSE L, ABREO MELWYN A, FENG YANGBO, PLOURDE, JR. ROBERT, KHASONOVA TATYANA V, DOUGLASS, III JAMES G
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creator TU CHI
ALFARO-LOPEZ LORENZO J
SHAVER SAMMY R
HARVEY DANIEL F
WATSON PAUL S
BOYER JOSE L
ABREO MELWYN A
FENG YANGBO
PLOURDE, JR. ROBERT
KHASONOVA TATYANA V
DOUGLASS, III JAMES G
description This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a non-nucleotide compound, preferably a P2Y12 receptor antagonist compound, wherein said amount is effective to inhibit platelet aggregation. The compounds useful for this invention include compounds of general Formulae I and III-XII, or salts, hydrates, and solvates thereof. The present invention also provides novel compounds of Formulae I and III-XII.
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subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMISTRY
DERIVATIVES THEREOF
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
SUGARS
TRAPPING
title Non-nucleotide composition for inhibiting platelet aggregation
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