Process for the manufacture of 3-hydroxy-N-alkyl-1-cycloalky1-6-alkyl-4-oxo-1,4-dihydropyridine-2-carboxamide and its related analogues

The present invention relates to a novel process for the preparation of 1-alkyl or 1-cycloalkyl derivatives of 3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxamide of formula (I). The process includes reacting an amine R2NH2 with a compound of formula (II) in a solution of metal hydroxide in water to g...

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Bibliographische Detailangaben
Hauptverfasser: LEUNG-TOUNG REGIS, LI WANREN, AGOSTINO SANDRA VITTORIA, TAM TIM FAT, SHAH BIRENKUMAR HASMUKHBHAI, ZHAO YANQING, WANG YINGSHENG
Format: Patent
Sprache:eng
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