Aminopyrimidine compounds and methods of use

The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwa...

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Hauptverfasser: PARAS NICK A, BRENNAN PAUL EDWARD, LIU GANG, RETZ DANIEL MARTIN, SMITH ADRIAN LEONARD, FILS FENEL F, RAINBEAU ELIZABETH
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creator PARAS NICK A
BRENNAN PAUL EDWARD
LIU GANG
RETZ DANIEL MARTIN
SMITH ADRIAN LEONARD
FILS FENEL F
RAINBEAU ELIZABETH
description The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Aminopyrimidine compounds and methods of use
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