Use of Acetylamino benzoic acid compounds for nonsense suppression and the treatment of disease

Use of Acetylamino benzoic acid compounds for nonsense suppression and the treatment of disease

Novel acetylamino benzoic acid compounds, methods of using and pharmaceutical compositions comprising an acetylamino benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-media...

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Hauptverfasser: ALMSTEAD NEIL G, WELCH ELLEN M, TAKASUGI JAMES JAN, RUBENSTEIN STEVEN MARC, BECKMANN HOLGER, WILDE RICHARD G
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator ALMSTEAD NEIL G
WELCH ELLEN M
TAKASUGI JAMES JAN
RUBENSTEIN STEVEN MARC
BECKMANN HOLGER
WILDE RICHARD G
description Novel acetylamino benzoic acid compounds, methods of using and pharmaceutical compositions comprising an acetylamino benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Use of Acetylamino benzoic acid compounds for nonsense suppression and the treatment of disease
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