Methods and pharmaceutical compositions for reliable achievement of acceptable serum testosterone levels

Methods and pharmaceutical compositions for reliable achievement of acceptable serum testosterone levels

The present invention relates to pharmaceutical compositions, formulated for injectable administration, which comprises a testosterone ester, in particularly testosterone undecanoate, in a vehicle comprising castor oil and a co-solvent. Upon injecting the compositions according to a particular admin...

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Hauptverfasser: INGWERSEN JAN-PETER, KUHNZ WILHELM, FRICKE SABINE, HUBLER DORIS
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator INGWERSEN JAN-PETER
KUHNZ WILHELM
FRICKE SABINE
HUBLER DORIS
description The present invention relates to pharmaceutical compositions, formulated for injectable administration, which comprises a testosterone ester, in particularly testosterone undecanoate, in a vehicle comprising castor oil and a co-solvent. Upon injecting the compositions according to a particular administration scheme, reliable levels of testosterone in serum in the normal physiological range is achieved for a long period. This allows for the use of the compositions in hormone replacement therapy and male contraception without concomitant monitoring of testosterone levels in serum by a physician.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Methods and pharmaceutical compositions for reliable achievement of acceptable serum testosterone levels
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