Pantoprazole multiparticulate formulations

Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a distintegrant; a sub coat which is comprised of hydro...

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Hauptverfasser: SAUNDERS RICHARD WILLIAM, VENKATA RAMANA RAO SRIPRIYA, NAGI ARWINDER, SHAH SYED M, TATAPUDY HANUMANTHARAO, FAWZI MAHDI, SINGH SHAILESH, HASAN SUMON A
Format: Patent
Sprache:eng
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Zusammenfassung:Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a distintegrant; a sub coat which is comprised of hydroxypropyl methylcellulose (hypromellose) and water, an enteric coat on the sub-coat, and a final seal coat over the enteric coat, which is composed of hydroxypropyl methylcellulose (hypromellose) and water.