Thieno-pyrimidine compounds having fungicidal activity
The present invention relates to thieno[2,3-d]-pyrimidine compounds having fungicidal activity. Specifically, the present invention relates to compounds having the Formula (I): wherein each R1, R2 and R3 is independently selected from the group consisting of H, halogen, and alkyl; A is selected from...
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Sprache: | eng |
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Zusammenfassung: | The present invention relates to thieno[2,3-d]-pyrimidine compounds having fungicidal activity. Specifically, the present invention relates to compounds having the Formula (I): wherein each R1, R2 and R3 is independently selected from the group consisting of H, halogen, and alkyl; A is selected from the group consisting of H and alkyl; W is selected from the group consisting of NH and O; D is selected from O, NH and S; E is (-C(O)-)p-R', wherein p is 0 or 1 and R' is selected from the group consisting of optionally substituted rings selected from phenyl. furanyl, pyridinyl, pyridinyl-N-oxide, pyrimidinyl, pyridazinyl, pyrazinyl, thiazolyl, triazinyl, thiadiazolyl, oxazolyl, isoxazolyl, thienopyrimidinyl, and pyrimidine fused with an aromatic or heteroaromatic ring selected from bejizene, oxazole, isoxazole, furan, thiazole, pyrimidine, pyridine, pyrrole, pyrazine, and thionhene; each ring being ontionally substituted with one or more substituents selected from the group consisting of alkyl, alkenyl, alkynyl, halogen, haloalkyl, alkoxy, haloalkoxy, nitro, cyano, alkylsulfonyl, alkylsulfoxide, alkylthio, alkoxyiminoalkyl, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, hydroxycarbonyl, phenyicarbonyl, forrnyl, hydrazidocarbonyl, amidoamino, pyrazolyl, triazolonyl, oxadiazolyl, phenyl, nyridinyl, and phenoxyalkyl; B is selected from the group consisting of halogen, alkyl, haloalkyl, and haloalkoxy; n is an integer from 0 to 3; and m is an integer from 0 to 4 with the proviso that when D is O or S and E is phenyl, then E is not further substituted with halogen. |
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