Labeled complementary oligonucleotides to detect oligonucleotide-linked ligands

Methods for determining the presence of an analyte in a sample are disclosed, in which a capture agent is bound to the analyte at a first epitope and a detection agent is bound at a second epitope, and in which the detection agent includes an oligonucleotide to which a labeled, complementary oligonu...

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Hauptverfasser: WALLACE ROBERT BRUCE, REDDY M. PARAMESWARA, BRILLHART KURT
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods for determining the presence of an analyte in a sample are disclosed, in which a capture agent is bound to the analyte at a first epitope and a detection agent is bound at a second epitope, and in which the detection agent includes an oligonucleotide to which a labeled, complementary oligonucleotide can be hybridized.