Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula I, wherein the substituents R1, R2, R3 and R4 have the meanings given in the description and also pharmaceutical compositions containing these compounds, in particu...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | MICHAELIS KATRIN KARIMI-NEJAD YASMIN MESSINGER JOSEF TURSKI LECHOSLAW IKONOMIDOU HRISSANTHI FISCHER YVAN PAHL AXEL HOEFER CONSTANZE ZIEGLER DIETER HOELTJE DAGMAR WESKE MICHAEL |
| description | Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula I, wherein the substituents R1, R2, R3 and R4 have the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US7452875B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US7452875B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US7452875B23</originalsourceid><addsrcrecordid>eNqNjDFOBDEMALehQMAfXIJECg5ORwsIREUD1Cdv4mMtEieKHYm9T_IlsgcPoLLsGc_x8H2XOORENs3RaRvV2JpRgCt37rGO-WvG-DnHC_Czj7mQWBcPROaIiSW7kWSPeyos5F4cejL2gJ4D-JxKbhL0EkrNnlQBJQCLUU0UGI0WEJo3hV2uYBNx7ScqWNE4y8EvE9bUu62HMf5WlResfRFDFpaP5TmdDkc7jEpnf_NkgKfHt4dnRyVvSUuvCNn2_XVzs17dbtb3q-t_KD8Lm2kf</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them</title><source>esp@cenet</source><creator>MICHAELIS KATRIN ; KARIMI-NEJAD YASMIN ; MESSINGER JOSEF ; TURSKI LECHOSLAW ; IKONOMIDOU HRISSANTHI ; FISCHER YVAN ; PAHL AXEL ; HOEFER CONSTANZE ; ZIEGLER DIETER ; HOELTJE DAGMAR ; WESKE MICHAEL</creator><creatorcontrib>MICHAELIS KATRIN ; KARIMI-NEJAD YASMIN ; MESSINGER JOSEF ; TURSKI LECHOSLAW ; IKONOMIDOU HRISSANTHI ; FISCHER YVAN ; PAHL AXEL ; HOEFER CONSTANZE ; ZIEGLER DIETER ; HOELTJE DAGMAR ; WESKE MICHAEL</creatorcontrib><description>Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula I, wherein the substituents R1, R2, R3 and R4 have the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20081118&DB=EPODOC&CC=US&NR=7452875B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20081118&DB=EPODOC&CC=US&NR=7452875B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MICHAELIS KATRIN</creatorcontrib><creatorcontrib>KARIMI-NEJAD YASMIN</creatorcontrib><creatorcontrib>MESSINGER JOSEF</creatorcontrib><creatorcontrib>TURSKI LECHOSLAW</creatorcontrib><creatorcontrib>IKONOMIDOU HRISSANTHI</creatorcontrib><creatorcontrib>FISCHER YVAN</creatorcontrib><creatorcontrib>PAHL AXEL</creatorcontrib><creatorcontrib>HOEFER CONSTANZE</creatorcontrib><creatorcontrib>ZIEGLER DIETER</creatorcontrib><creatorcontrib>HOELTJE DAGMAR</creatorcontrib><creatorcontrib>WESKE MICHAEL</creatorcontrib><title>Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them</title><description>Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula I, wherein the substituents R1, R2, R3 and R4 have the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDFOBDEMALehQMAfXIJECg5ORwsIREUD1Cdv4mMtEieKHYm9T_IlsgcPoLLsGc_x8H2XOORENs3RaRvV2JpRgCt37rGO-WvG-DnHC_Czj7mQWBcPROaIiSW7kWSPeyos5F4cejL2gJ4D-JxKbhL0EkrNnlQBJQCLUU0UGI0WEJo3hV2uYBNx7ScqWNE4y8EvE9bUu62HMf5WlResfRFDFpaP5TmdDkc7jEpnf_NkgKfHt4dnRyVvSUuvCNn2_XVzs17dbtb3q-t_KD8Lm2kf</recordid><startdate>20081118</startdate><enddate>20081118</enddate><creator>MICHAELIS KATRIN</creator><creator>KARIMI-NEJAD YASMIN</creator><creator>MESSINGER JOSEF</creator><creator>TURSKI LECHOSLAW</creator><creator>IKONOMIDOU HRISSANTHI</creator><creator>FISCHER YVAN</creator><creator>PAHL AXEL</creator><creator>HOEFER CONSTANZE</creator><creator>ZIEGLER DIETER</creator><creator>HOELTJE DAGMAR</creator><creator>WESKE MICHAEL</creator><scope>EVB</scope></search><sort><creationdate>20081118</creationdate><title>Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them</title><author>MICHAELIS KATRIN ; KARIMI-NEJAD YASMIN ; MESSINGER JOSEF ; TURSKI LECHOSLAW ; IKONOMIDOU HRISSANTHI ; FISCHER YVAN ; PAHL AXEL ; HOEFER CONSTANZE ; ZIEGLER DIETER ; HOELTJE DAGMAR ; WESKE MICHAEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US7452875B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2008</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MICHAELIS KATRIN</creatorcontrib><creatorcontrib>KARIMI-NEJAD YASMIN</creatorcontrib><creatorcontrib>MESSINGER JOSEF</creatorcontrib><creatorcontrib>TURSKI LECHOSLAW</creatorcontrib><creatorcontrib>IKONOMIDOU HRISSANTHI</creatorcontrib><creatorcontrib>FISCHER YVAN</creatorcontrib><creatorcontrib>PAHL AXEL</creatorcontrib><creatorcontrib>HOEFER CONSTANZE</creatorcontrib><creatorcontrib>ZIEGLER DIETER</creatorcontrib><creatorcontrib>HOELTJE DAGMAR</creatorcontrib><creatorcontrib>WESKE MICHAEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MICHAELIS KATRIN</au><au>KARIMI-NEJAD YASMIN</au><au>MESSINGER JOSEF</au><au>TURSKI LECHOSLAW</au><au>IKONOMIDOU HRISSANTHI</au><au>FISCHER YVAN</au><au>PAHL AXEL</au><au>HOEFER CONSTANZE</au><au>ZIEGLER DIETER</au><au>HOELTJE DAGMAR</au><au>WESKE MICHAEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them</title><date>2008-11-18</date><risdate>2008</risdate><abstract>Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula I, wherein the substituents R1, R2, R3 and R4 have the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US7452875B2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T08%3A24%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=MICHAELIS%20KATRIN&rft.date=2008-11-18&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS7452875B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |