High affinity thiophene-based and furan-based kinase ligands
Inhibitors of cyclin dependent kinase 2, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of...
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| creator | WINDSOR WILLIAM T PARRY DAVID A SHIPPS, JR. GERALD W MAYHOOD TODD W ZHANG RUMIN CURRAN PATRICK J MCNEMAR CHARLES W SIDDIQUI M. ARSHAD DENG YONGQI LEES EMMA M ZHAO LIANYUN |
| description | Inhibitors of cyclin dependent kinase 2, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making CDK-2 inhibitor compounds, methods of inhibiting CDK-2, and methods for treating disease or disease symptoms. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | High affinity thiophene-based and furan-based kinase ligands |
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