Antagonistic peptides of prostaglandin E2 receptor subtype EP4

Antagonistic peptides of prostaglandin E2 receptor subtype EP4

Antagonistic peptides of prostaglandin E2 receptor subtype EP4 and their use in the treatment or prevention of medical conditions associated with oligouric nephropathy, bone resorption, abnormal intestinal crypt cell proliferation or patency of the ductus arteriosus and the like are provided herein....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ABRAN DANIEL, PERI KRISHNA G, MOFFETT SERGE, BERGERON ANNIE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator ABRAN DANIEL
PERI KRISHNA G
MOFFETT SERGE
BERGERON ANNIE
description Antagonistic peptides of prostaglandin E2 receptor subtype EP4 and their use in the treatment or prevention of medical conditions associated with oligouric nephropathy, bone resorption, abnormal intestinal crypt cell proliferation or patency of the ductus arteriosus and the like are provided herein. The antagonistic peptides of the present invention can include the following formula: X-A-RnYm wherein "X" is a hydrogen atom or an amine protecting group producing a carbamate or an amide when reacting with the amine; "A" is L-(4,4')-biphenylalanine or D-(4,4')-biphenylalanine; "R" is an amino acid selected from the group consisting of threonine, serine, tyrosine, glutamic acid, alanine, leucine and glycine; "Y" is lysine; "n" is an integer ranging from 5 to 7; and "m" is an integer ranging from 0 to 2.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US7414029B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US7414029B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US7414029B23</originalsourceid><addsrcrecordid>eNrjZLBzzCtJTM_PyywuyUxWKEgtKMlMSS1WyE9TKCjKLwZK5STmpWTmKbgaKRSlJgOl84sUikuTSioLUhVcA0x4GFjTEnOKU3mhNDeDgptriLOHbmpBfnxqcUFicmpeakl8aLC5iaGJgZGlk5ExEUoA9AYwCg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Antagonistic peptides of prostaglandin E2 receptor subtype EP4</title><source>esp@cenet</source><creator>ABRAN DANIEL ; PERI KRISHNA G ; MOFFETT SERGE ; BERGERON ANNIE</creator><creatorcontrib>ABRAN DANIEL ; PERI KRISHNA G ; MOFFETT SERGE ; BERGERON ANNIE</creatorcontrib><description>Antagonistic peptides of prostaglandin E2 receptor subtype EP4 and their use in the treatment or prevention of medical conditions associated with oligouric nephropathy, bone resorption, abnormal intestinal crypt cell proliferation or patency of the ductus arteriosus and the like are provided herein. The antagonistic peptides of the present invention can include the following formula: X-A-&lt;img id="PRIVATE-USE-CHARACTER-00001" he="7.20mm" wi="8.47mm" file="US07414029-20080819-Parenopenst.TIF" alt="private use character Parenopenst" img-content="character" img-format="tif" /&gt;R&lt;img id="PRIVATE-USE-CHARACTER-00002" he="7.20mm" wi="8.47mm" file="US07414029-20080819-Parenclosest.TIF" alt="private use character Parenclosest" img-content="character" img-format="tif" /&gt;nYm wherein "X" is a hydrogen atom or an amine protecting group producing a carbamate or an amide when reacting with the amine; "A" is L-(4,4')-biphenylalanine or D-(4,4')-biphenylalanine; "R" is an amino acid selected from the group consisting of threonine, serine, tyrosine, glutamic acid, alanine, leucine and glycine; "Y" is lysine; "n" is an integer ranging from 5 to 7; and "m" is an integer ranging from 0 to 2.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20080819&amp;DB=EPODOC&amp;CC=US&amp;NR=7414029B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20080819&amp;DB=EPODOC&amp;CC=US&amp;NR=7414029B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ABRAN DANIEL</creatorcontrib><creatorcontrib>PERI KRISHNA G</creatorcontrib><creatorcontrib>MOFFETT SERGE</creatorcontrib><creatorcontrib>BERGERON ANNIE</creatorcontrib><title>Antagonistic peptides of prostaglandin E2 receptor subtype EP4</title><description>Antagonistic peptides of prostaglandin E2 receptor subtype EP4 and their use in the treatment or prevention of medical conditions associated with oligouric nephropathy, bone resorption, abnormal intestinal crypt cell proliferation or patency of the ductus arteriosus and the like are provided herein. The antagonistic peptides of the present invention can include the following formula: X-A-&lt;img id="PRIVATE-USE-CHARACTER-00001" he="7.20mm" wi="8.47mm" file="US07414029-20080819-Parenopenst.TIF" alt="private use character Parenopenst" img-content="character" img-format="tif" /&gt;R&lt;img id="PRIVATE-USE-CHARACTER-00002" he="7.20mm" wi="8.47mm" file="US07414029-20080819-Parenclosest.TIF" alt="private use character Parenclosest" img-content="character" img-format="tif" /&gt;nYm wherein "X" is a hydrogen atom or an amine protecting group producing a carbamate or an amide when reacting with the amine; "A" is L-(4,4')-biphenylalanine or D-(4,4')-biphenylalanine; "R" is an amino acid selected from the group consisting of threonine, serine, tyrosine, glutamic acid, alanine, leucine and glycine; "Y" is lysine; "n" is an integer ranging from 5 to 7; and "m" is an integer ranging from 0 to 2.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLBzzCtJTM_PyywuyUxWKEgtKMlMSS1WyE9TKCjKLwZK5STmpWTmKbgaKRSlJgOl84sUikuTSioLUhVcA0x4GFjTEnOKU3mhNDeDgptriLOHbmpBfnxqcUFicmpeakl8aLC5iaGJgZGlk5ExEUoA9AYwCg</recordid><startdate>20080819</startdate><enddate>20080819</enddate><creator>ABRAN DANIEL</creator><creator>PERI KRISHNA G</creator><creator>MOFFETT SERGE</creator><creator>BERGERON ANNIE</creator><scope>EVB</scope></search><sort><creationdate>20080819</creationdate><title>Antagonistic peptides of prostaglandin E2 receptor subtype EP4</title><author>ABRAN DANIEL ; PERI KRISHNA G ; MOFFETT SERGE ; BERGERON ANNIE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US7414029B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2008</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>ABRAN DANIEL</creatorcontrib><creatorcontrib>PERI KRISHNA G</creatorcontrib><creatorcontrib>MOFFETT SERGE</creatorcontrib><creatorcontrib>BERGERON ANNIE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ABRAN DANIEL</au><au>PERI KRISHNA G</au><au>MOFFETT SERGE</au><au>BERGERON ANNIE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Antagonistic peptides of prostaglandin E2 receptor subtype EP4</title><date>2008-08-19</date><risdate>2008</risdate><abstract>Antagonistic peptides of prostaglandin E2 receptor subtype EP4 and their use in the treatment or prevention of medical conditions associated with oligouric nephropathy, bone resorption, abnormal intestinal crypt cell proliferation or patency of the ductus arteriosus and the like are provided herein. The antagonistic peptides of the present invention can include the following formula: X-A-&lt;img id="PRIVATE-USE-CHARACTER-00001" he="7.20mm" wi="8.47mm" file="US07414029-20080819-Parenopenst.TIF" alt="private use character Parenopenst" img-content="character" img-format="tif" /&gt;R&lt;img id="PRIVATE-USE-CHARACTER-00002" he="7.20mm" wi="8.47mm" file="US07414029-20080819-Parenclosest.TIF" alt="private use character Parenclosest" img-content="character" img-format="tif" /&gt;nYm wherein "X" is a hydrogen atom or an amine protecting group producing a carbamate or an amide when reacting with the amine; "A" is L-(4,4')-biphenylalanine or D-(4,4')-biphenylalanine; "R" is an amino acid selected from the group consisting of threonine, serine, tyrosine, glutamic acid, alanine, leucine and glycine; "Y" is lysine; "n" is an integer ranging from 5 to 7; and "m" is an integer ranging from 0 to 2.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US7414029B2
source esp@cenet
subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Antagonistic peptides of prostaglandin E2 receptor subtype EP4
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T22%3A26%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ABRAN%20DANIEL&rft.date=2008-08-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS7414029B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true