Methods and compositions for genomic modification

The present invention provides methods of site-specifically integrating a polynucleotide sequence of interest in a genome of a eucaryotic cell, as well as, enzymes, polypeptides, and a variety of vector constructs useful therefore. In the method, a targeting construct comprises, for example, (i) a f...

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1. Verfasser: CALOS MICHELE PAMELA
Format: Patent
Sprache:eng
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