Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes

The present invention relates to a melanin concentrating hormone antagonist compound of formula I: (I); or a pharmaceutically acceptable salt, solvate, enantiomer or prodrug thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.

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Hauptverfasser: AMMENN JOCHEN, SLIEKER LAWRENCE JOHN, SNYDER NANCY JUNE, ROBERTSON MICHAEL ALAN, KINNICK MICHAEL DEAN, MORIN, JR. JOHN MICHAEL, GILLIG JAMES RONALD, SAVIN KENNETH ALLEN, SCHOTTEN THEO, HEINZ LAWRENCE JOSEPH, LAI YEN-SHI, OTT CARSTEN, HIPSKIND PHILIP ARTHUR, NIXON JAMES ARTHUR
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creator AMMENN JOCHEN
SLIEKER LAWRENCE JOHN
SNYDER NANCY JUNE
ROBERTSON MICHAEL ALAN
KINNICK MICHAEL DEAN
MORIN, JR. JOHN MICHAEL
GILLIG JAMES RONALD
SAVIN KENNETH ALLEN
SCHOTTEN THEO
HEINZ LAWRENCE JOSEPH
LAI YEN-SHI
OTT CARSTEN
HIPSKIND PHILIP ARTHUR
NIXON JAMES ARTHUR
description The present invention relates to a melanin concentrating hormone antagonist compound of formula I: (I); or a pharmaceutically acceptable salt, solvate, enantiomer or prodrug thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes
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