Guinea pig proteinase-activated receptor 4 and its activating peptide

This invention relates to nucleic acid encoding guinea pig PAR 4 and to the protein encoded thereby. The guinea pig DNA and protein are useful for the development of models of human platelet aggregation. The invention further relates to an animal model to assess the role of PAR antagonists in thromb...

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Hauptverfasser: ADDO MICHAEL F, DERIAN CLAUDIA K, DARROW ANDREW L, ANDRADE-GORDON PATRICIA
Format: Patent
Sprache:eng
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Zusammenfassung:This invention relates to nucleic acid encoding guinea pig PAR 4 and to the protein encoded thereby. The guinea pig DNA and protein are useful for the development of models of human platelet aggregation. The invention further relates to an animal model to assess the role of PAR antagonists in thrombosis.