Triazole derivative

The invention relates to a triazole derivative with an activity inhibiting glycine transporter and for use as a pharmaceutical drug, and a novel triazole derivative. The inventive triazole derivative has an excellent activity inhibiting glycine transporter and is useful as a therapeutic agent of dem...

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Hauptverfasser: GREINER HARTMUT, SUGANE TAKASHI, MAENO KYOICHI, MORITA TAKUMA, HAMAGUCHI WATARU, ARLT MICHAEL, KIMIZUKA TETSUYA, SUZUKI TAKESHI, MIYATA JUNJI, KOHARA ATSUYUKI, TOBE TAKAHIKO, SHIMADA ITSURO
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creator GREINER HARTMUT
SUGANE TAKASHI
MAENO KYOICHI
MORITA TAKUMA
HAMAGUCHI WATARU
ARLT MICHAEL
KIMIZUKA TETSUYA
SUZUKI TAKESHI
MIYATA JUNJI
KOHARA ATSUYUKI
TOBE TAKAHIKO
SHIMADA ITSURO
description The invention relates to a triazole derivative with an activity inhibiting glycine transporter and for use as a pharmaceutical drug, and a novel triazole derivative. The inventive triazole derivative has an excellent activity inhibiting glycine transporter and is useful as a therapeutic agent of dementia, schizophrenia, cognitive disorders, or cognitive disorders involved in various diseases such as Alzheimer disease, Parkinson's disease, or Huntington disease or the like, or spasm involved in diseases such as nerve degenerative diseases and cerebrovascular disorders, or the like. Particularly, the pharmaceutical drug is useful for the amelioration of learning disability of dementia and the like.
format Patent
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Triazole derivative
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